Hygeia journal for drugs and medicines


Antiulcer activity of the Leaf ethanolic extract of Mimosa pudica in Rats

Hygeia.J.D.Med.4(1),April 2012-October 2012,34-40

Authors : 
Elango.V1, Carolin Oliver1 and Raghu, P.S.2*


1. Dept of Siddha Medicine, Faculty of Sciences, Tamil university, Thanjavur-613 010, Tamilnadu, India

2. Mohammadia Institute of Pharmacy, Arambula, Khammam-507163, Andhra Pradesh, India.     


Article history: 

Received: 19 Jan. 2012

Revised: 25 Jan. 2012,

Accepted: 15 February 2012

Available online: 05 April 2012



PlanThe present study was designed to investigate the antiulcer potential of ethanolic extract of Mimosa pudica leaves.

MethodologyAntiulcer activity was evaluated by pylorus ligation, aspirin and ethanol induced ulcer models. The ethanolic extract of the leaves of Mimosa pudica was given by oral route at a dose of 100 mg/kg b.w.

OutcomeEthanolic extract of Mimosa pudica, dose dependently reduce, the total acidity, ulcer index, and an increase in pH of gastric juice in  pylorus ligated ulcer model. Extract of Mimosa pudica may be useful as a natural antioxidant in the treatment of ulcer.

Keywords: Antiulcer Activity, Mimosa pudica, leaf ethanolic extract

Article outline


2.Materials and methods


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