Hygeia.J.D.Med.8(2) November 2016 - May 2017

Abstract

Antioxidant potential of Cedrela odorata stems extracts and Bio active Phytoconstituents

Hygeia.J.D.Med.6(1)2014; 25-30.

Khaled Rashed

Pharmacognosy Department, National Research Centre, Dokki, Giza,Egypt.

Article history:Received: 12 January 2014,   revised: 4 February 2014, accepted: 17 February 2014, Available online: 3 April 2014

 

 

Plan and Methodology: This study evaluated antioxidant activity of Cedrelaodorata stems extracts and also investigated the bioactive phytoconstituents in the bioactive extract.N-hexanedichloromethane (DCM),ethyl acetate and methanol 80% extract were tested for free radical scavenging activity on model reaction with stable 2,2-diphenyl-1-picrylhydrazyl radical (DPPH).

Outcome: The results showed that dichloromethane was the most active one as antioxidant agent and phytochemical analysis of the extract revealed that it is rich with triterpenes.Chromatographic separation of that extract resulted in the isolation and identification of two triterpenic acids, Oleanolic and ursolic acids and luteolin. The results may help to discover new chemical classes of natural antioxidants substances that could serve as selective agents for infectious diseases.

Keywords: Cedrela odorata, stems, antioxidant effect, phytochemicals.

  

For Correspondence: khalednabih2015@yahoo.co.uk
Contact: 01003642233
Rid:J-3090-2013    

Citation:Khaled Rashed. Antioxidant potential of Cedrela odorata stems extracts and Bioactive Phytoconstituents. Hygeia.J.D.Med2014;6(1):25-30. Available from http://www.hygeiajournal.com .ArticleID- Hygeia.J.D.Med/119/14.  D.O.I:10.15254/H.J.D.Med.6.2014.119


Chemical structures of the compounds isolated from Cedrela odorata stems

                                                                    

             


                Oleanolic acid                                          Luteolin                                               Ursolic acid


Copyright@ 2014 Hygeia journal for drugs and medicines, 2229 3590, 0975 6221.
This is an open-access article distributed under the terms of the Creative Commons Attribution License.

Hygeia J. D. Med.





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