Antioxidant potential of Cedrela odorata stems extracts and Bio active Phytoconstituents
Pharmacognosy Department, National Research Centre, Dokki, Giza,Egypt.
Article history:Received: 12 January 2014, revised: 4 February 2014, accepted: 17 February 2014, Available online: 3 April 2014
Plan and Methodology: This study evaluated antioxidant activity of Cedrelaodorata stems extracts and also investigated the bioactive phytoconstituents in the bioactive extract.N-hexane, dichloromethane (DCM),ethyl acetate and methanol 80% extract were tested for free radical scavenging activity on model reaction with stable 2,2-diphenyl-1-picrylhydrazyl radical (DPPH).
Outcome: The results showed that dichloromethane was the most active one as antioxidant agent and phytochemical analysis of the extract revealed that it is rich with triterpenes.Chromatographic separation of that extract resulted in the isolation and identification of two triterpenic acids, Oleanolic and ursolic acids and luteolin. The results may help to discover new chemical classes of natural antioxidants substances that could serve as selective agents for infectious diseases.
Keywords: Cedrela odorata, stems, antioxidant effect, phytochemicals.
For Correspondence: firstname.lastname@example.org
Citation:Khaled Rashed. Antioxidant potential of Cedrela odorata stems extracts and Bioactive Phytoconstituents. Hygeia.J.D.Med2014;6(1):25-30. Available from http://www.hygeiajournal.com .ArticleID- Hygeia.J.D.Med/119/14. D.O.I:10.15254/H.J.D.Med.6.2014.119
Chemical structures of the compounds isolated from Cedrela odorata stems
Oleanolic acid Luteolin Ursolic acid
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