Abstract
Simultaneous Determination of Curcumin and Gefitinib in Pure Form by using UV Spectrophotometric Method
Hygeia.J.D.Med. 2017;9 (1):1-8
DOI:10.15254/H.J.D.Med.9.2017.160
Sagar Savale
R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, 425405, MS, India
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ABSTRACT
Plan: Development and Validation of a method for the UV simultaneous determination of curcumin and Gefitinib.
Preface: U.V Spectrophotometric method has been widely employed in the determination of individual components in a mixture or fixed dose combination.For the ternary mixture containing Curcumin and Gefitinib, no spectrophotometric method for simultaneous evaluation has been reported so far.Thus our aim is to develop simultaneous equation method for estimation of the ternary mixture using U.V spectrophotometry.
Methodology: The method was validated as per ICHguidelines. The recovery studies confirmed the accuracy and precision of the method.
Outcome: It was successfully applied for the analysis of the drug in bulk and could be effectively used for the routine analysis
Keywords: Curcumin, Gefitinib, simultaneous estimation, UV spectrophotometric method
Correspondence
Sagar Savale M.Pharm, Department of Pharmaceutics, R. C. Patel Institute of Pharmaceutical Education & Research, Shirpur, 425405, MS, India. MobileNo: +91 9960885333,
Article History: Received: 12 January 2017, Revised: 9 February, 2017Accepted: 25 March 2017, Available online: 1 July 2017
Article citation
Sagar Savale.Simultaneous determination of curcumin and gefitinib in pure form by using the UVspectrophotometric method. Hygeia.J.D.Med 2017; 9(1):1-8. Available from http://www.hygeiajournal.com, DOI: 10.15254/H.J.D.Med.9.2017.160
FTIR Spectra of curcumin + Gefitinib