Hygeia.J.D.Med.9(1) July 2017 - December 2017

Abstract

Design and in-vitro Evaluation of Gelatin Microspheres of Salbutamol Sulphate
Hygeia J. D. Med. Vol.1 (1) 2009, 17-20
(ISSN 0975 6221)

Type of Article 
Research Article

Authors 
Suja .C. Jayan* , Sandeep A.V , Mohammed Rifash , Mareema .C.M , Shamseena. S.

Affiliation 
Department of Pharmaceutics,Crescent College of Pharmaceutical Sciences, Madayipara, Payangadi, Kannur, Kerala

Abstract 

In the present study, gelatin microspheres containing Salbutamol sulphate were prepared by coacervation phase separation method and characterized by optical microscopy and scanning electron microscopy. The microspheres were analyzed for drug entrapment, and in vitro release pattern. The different batches of microspheres were prepared by altering drug : polymer ratio and cross linking with glutaraldehyde The size of microspheres was in the range of 5.6m- 22.4 m and the average diameter was found to be 12.34 m. They were spherical in shape as evidenced by scanning electron microscopic photographs. The percent drug entrapment was up to 80% and they could sustain drug release over a period of 8 ½ hours.


Keywords: Salbutamol sulphate, microspheres, gelatin, glutaraldehyde.
 
For contact: 9495458557
*
sujajayan@rediffmail.com
© 2009 Hygeia journal for drugs and medicines. 
 All rights reserved. 0975 6221

Hygeia J. D. Med.





Videos

  • watch Video
    Collagen Mimetic Peptides
  • watch Video
    Mechanisms and secrets of Alzheimer's disease...
  • watch Video
    Immunotherapy to fight cancer
  • watch Video
    Food Safety Emergency Prevention