Abstract
DRUG USAGE IN PREGNANCY
Hygeia.J.D.Med.Vol.2 (2), 2010,1-4.
Type of article: PHARMACEUTICAL EDUCATION
Author: Siyad.A.R
Affiliation:
Crescent College of Pharmaceutical Sciences ,Payangadi.P.O , Kannur, Kerala , India 670358 .
Available online : August 12, .2010
The use of drugs during pregnancy is a question of fine balance; no harm should be allowed to be fall on the baby because of the drug, and no harm must come to the mother or baby because a disease is being inadequately treated. Knowledge of the harmful effects of drugs on the foetus by the thalidomide disaster was followed by a reduction of the use of drugs by pregnant women.
DRUGS USAGE DURING PREGNANCY
Category-A
Drugs which have been taken by a large no. of pregnant women ofchildbearing age without any proven increase in the frequency of malformationsor other direct/indirect harmful effects on the foetus having been observed
Category-B1
Drugs which, occurring to their pharmacological effects, have caused ormay be suspected of causing harmful effects on the human foetus or neonatewithout causing malformations. There effects may be reversible, have been taken by only a limited No. of preant women & women of childbearing age, without an increase in the frequency ofmalformation or other direct/indirect harmful effects on the human foetushaving been observed. Studies in animals have not shown evidence of anoccurrence of foetal damage.
Category-B2
Drugs which have been taken by only a limited No. of pregnant women ofchildbearing age without an in frequency of malformation or otherdirect/indirect harmful effects on the human foetus having been observed. Studies in animals are inadequate or may be lacking, but availabledata show no evidence of an occurrence of foetal damage.
Category-B3
Studies in animals have shown evidence of an occurrence of foetaldamage, the significance of which is considered uncertain in humans.
Category-D
Drugs which have caused & suspected to have caused or may beexpected to cause, an increased incidence of human foetal malformations / irreversible damage. These drugs also have adverse pharmacological effects.
Category –X
Drugs which have a high risk of causing permanent damage to the fetusthat they should not be used in pregnancy when there is a possibility of pregnancy.
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Author for Correspondence:
siyadmpharm@yahoo.co
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