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Phytochemical studies and pharmacological screening of Sida rhombifolia Linn.

Hygeia.J.D.Med. 2013; 5(1):19-22.

R Sundaraganapathy1, V Niraimathi2, Ananda Thangadurai*1, M Jambulingam1, B Narasimhan3 and Aakash Deep3

1. Swamy Vivekananda College of Pharmacy, Elayampalayam, Tiruchengode-637 205, India

2. College of Pharmacy, Madras Medical College, Chennai
3. Faculty of Pharmaceutical Sciences, Maharishi Dayanand University, Rohtak – 124 001, India.

Article history: Received: 20 December 2012, revised: 14 February 2013, accepted: 25February 2013, Available online: 3 April 2013

Abstract

Plan: Anti-anxiety activity of Sida rhombifolia Linn.

Prologue: Sida rhombifolia commonly called Bala or Atibala is claimed by folklore for various ailments like rheumatism, seminal weakness, and diarrhea. Earlier studies on the ethanolic extract of the roots (SRE) revealed a significant, antioxidant, antimicrobial,anti-inflammatory, hepatoprotective and antibacterial activity. The present study was designed to evaluate anti-anxiety activity of powdered whole plant extracts of Sida rhombifolia Linn. viz petroleum ether and ethanol.

Methodology: Anti-anxiety activity of Sida rhombifolia Linn. were studied by using Elevated Plus Maze (EPM) model in albino mice.

Outcome: Albino mice were treated orally with dose 300 mg/kg of the extract and behavior was observed on the EPM. Diazepam (2mg/kg, P.O) was used as a positive control l. Result showed that alcoholic extract was found to produce very significant t result. Hence, this plant may be developed as a potential useful anti anxiety agent

Keywords: Sida rhombifolia Linn., Anti-anxiety activity

R Sundaraganapathy, V Niraimathi, Ananda Thangadurai, M Jambulingam, B Narasimhan and Aakash Deep. Phytochemical studies and pharmacological screening of Sida rhombifolia Linn. Hygeia.J.D.Med. 2013; 5(1):19-22. Available from http://www.hygeiajournal.com / Article ID- Hygeia.J.D.Med/84/13.